What are the chances that children or other family members of people with AMD will also be affected? The late onset forms of Macular Degeneration are not known to be inherited in a straightforward pattern such as autosomal dominant or recessive. However, familial patters have been observed, indicating that inheritance is involved to some extent. Some surveys have estimated that 15 to 20 percent of AMD patients have one or more first-degree relatives who are also affected. AMD presents a special challenge for genetic researchers because it is difficult to determine the exact role of genetics when a disease occurs late in life. Genetic research is a major emphasis of Retina International and a number of genes associated with AMD have already been identified. From these and other studies, scientists hope to learn more about the relationship between genes and Macular Degeneration. Members of Retina South Africa will receive priority for consideration in research projects.

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