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Is Retinal Degeneration inherited?
In most cases the answer is yes. The most common form of inheritance is
called recessive. In this type both the parents carry the genes which
causes RP. They themselves are unaffected but there is a 25% chance
that their children will have RP.
Another form of RP inheritance is
X-linked. In X-linked RP, females carry the gene causing RP. When
a female carrier marries an unaffected male, then there is a 50%
chance that their sons will be affected, and a 50% chance that their
daughters will be carriers.
X-linked RP is the one form for which
carriers can often be detected. In X-linked RP when an affected male
marries a non-carrier female, their sons will not be affected but all
their daughters will be carriers.
There is also a dominant form of RP
which can strike in every generation of a family. Since RP runs in
families, all members in an affected family are urged to have a
thorough eye examination. When planning a family, expert genetic
counselling should be sought.
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